COX-2/5-LOX-IN-1
Product Specifications
CAS Number
2410384-50-6
Target
Others, COX
Related Pathways
Immunology/Inflammation, Others, Neuroscience
Bioactivity
COX-2/5-LOX-IN-1 (compound 3a), a benzothiophen-2-yl pyrazole carboxylic acid derivative, is a potent dual inhibitor of COX-2 and 5-LOX, exhibiting superior analgesic and anti-inflammatory properties compared to Celecoxib and Indomethacin. It demonstrates strong inhibitory activity against COX-1, COX-2, and 5-LOX, with IC50 values of 12.13 μM, 0.4 μM, and 4.96 μM, respectively [1].
Smiles
C(O)(=O)C=1C=C(N(N1)C2=CC=C(S(N)(=O)=O)C=C2)C=3SC(Cl)=CC3
Molecular Formula
C14H10ClN3O4S2
Molecular Weight
383.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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