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Anticancer agent 56

Product Specifications

CAS Number

2241915-59-1

Target

Reactive Oxygen Species, Caspase, Apoptosis, Bcl-2 Family, Others

Related Pathways

Proteases/Proteasome, Immunology/Inflammation, NF-κB, Others, Apoptosis, Metabolism

Bioactivity

Anticancer agent 56 (compound 4d) is a powerful anti-cancer compound with favorable drug-like properties, showing significant anticancer activity against multiple cancer cell lines with an IC50 value of less than 3 μM. It exerts its effects by causing cell cycle arrest at the G2/M phase and activating the mitochondrial apoptosis pathway, inducing the accumulation of reactive oxygen species (ROS), upregulating BAX, downregulating Bcl-2, and triggering the activation of caspases 3, 7, and 9 [1].

Smiles

CC=1N(N=NC1C(/C=C/C2=CC(OC)=C(OC)C=C2)=O)C3=CC=C(Cl)C=C3

Molecular Formula

C20H18ClN3O3

Molecular Weight

383.83

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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