SBI-581
Product Specifications
Target
Others, Serine Protease
Related Pathways
Others, Proteases/Proteasome
Bioactivity
SBI-581 is an orally active, potent selective inhibitor of serine-threonine kinase TAO3, with an IC 50 of 42 nM. It effectively promotes the accumulation of TKS5α at RAB11-positive vesicles and inhibits the formation of invadopodia. Additionally, SBI-581 exhibits reasonable pharmacokinetics in mice when administered via IP injection, demonstrating significant antitumor activity [1].
Molecular Formula
C24H21N3O2
Molecular Weight
383.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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