What is the catalog number for SBI-581?

The catalog number for SBI-581 is T61663.

What sizes are available for SBI-581?

SBI-581 is available in the following size(s): 25 mg, 50 mg, 100 mg.

How many pack sizes does SBI-581 come in?

SBI-581 is available in 3 different pack sizes.

SBI-581 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures SBI-581?

SBI-581 is manufactured by Molfinity.

What is the estimated delivery time for SBI-581?

Estimated delivery time for SBI-581 is approximately 10 business day(s), depending on your location.

SBI-581

Product Specifications

Target

Others, Serine Protease

Related Pathways

Others, Proteases/Proteasome

Bioactivity

SBI-581 is an orally active, potent selective inhibitor of serine-threonine kinase TAO3, with an IC 50 of 42 nM. It effectively promotes the accumulation of TKS5α at RAB11-positive vesicles and inhibits the formation of invadopodia. Additionally, SBI-581 exhibits reasonable pharmacokinetics in mice when administered via IP injection, demonstrating significant antitumor activity [1].