TYK2-IN-11
Product Specifications
CAS Number
2757009-40-6
Target
JAK, Others
Related Pathways
Angiogenesis, JAK/STAT signaling, Stem Cells, Others, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors
Bioactivity
TYK2-IN-11 (Compound 5B) is a potent and selective inhibitor of Tyk-2, with IC50 values of 0.016 nM for TYK2-JH2 and 0.31 nM for JAK1-JH2. This compound shows potential for advancing research in inflammatory and autoimmune diseases [1].
Smiles
N(C=1C(=CN=C(NC(C)=O)C1)C2=CC=CC=N2)C=3N=C(S(C)(=O)=O)C=CC3
Molecular Formula
C18H17N5O3S
Molecular Weight
383.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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