Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

EGFR-IN-52

Product Specifications

CAS Number

454436-75-0

Target

EGFR, Apoptosis, Others

Related Pathways

Others, Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Apoptosis

Bioactivity

EGFR-IN-52 (Compound 4) is a highly effective inhibitor of the epidermal growth factor receptor (EGFR) with IC50 values of 0.358, 86.02, and 432.67 μM against EGFR, EGFR L858R-TK, and EGFR T790M-TK, respectively. Additionally, it demonstrates potent cytotoxic effects on cancer cell lines and triggers apoptosis [1].

Smiles

CN1N(C(=O)C(NC(=S)NC2=CC3=C(OCO3)C=C2)=C1C)C1=CC=CC=C1

Molecular Formula

C19H18N4O3S

Molecular Weight

382.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

2- (3-butoxyphenyl) -6-chloroquinoline-4-carbonyl chloride
sc-320557 100 mg

2- (3-butoxyphenyl) -6-chloroquinoline-4-carbonyl chloride

Sign In for Pricing
View Details
MRGBP siRNA (Mouse)
orb1840324-01 15 nmol

MRGBP siRNA (Mouse)

Sign In for Pricing
View Details
MRGBP siRNA (Mouse)
orb1840324-02 30 nmol

MRGBP siRNA (Mouse)

Sign In for Pricing
View Details
Cd28 ORF Vector (Rat) (pORF)
ORF064639 1.0 µg DNA

Cd28 ORF Vector (Rat) (pORF)

Sign In for Pricing
View Details
CHMP2B Rabbit Monoclonal Antibody [Clone ID: 23GB3070]
TA424651 100 µL

CHMP2B Rabbit Monoclonal Antibody [Clone ID: 23GB3070]

Sign In for Pricing
View Details
WDR1 Peptide - N-terminal region
MBS3230731-01 0.1 mg

WDR1 Peptide - N-terminal region

Sign In for Pricing
View Details