Vonoprazan hydrochloride
Product Specifications
CAS Number
1957202-44-6
Target
Proton pump, Others, Antibacterial
Related Pathways
Others, Membrane transporter/Ion channel, Microbiology/Virology
Bioactivity
Vonoprazan hydrochloride, a proton pump inhibitor (PPI), effectively functions as a potassium-competitive acid blocker (P-CAB) with potent antisecretory properties. It significantly inhibits H+, K+-ATPase activity in porcine gastric microsomes, displaying an IC50 of 19 nM at pH 6.5. Developed primarily for researching acid-related conditions such as gastroesophageal reflux disease and peptic ulcer disease, vonoprazan hydrochloride also aids in the eradication of Helicobacter pylori [1] [2] [3].
Smiles
Cl.CNCc1cc(-c2ccccc2F)n(c1)S(=O)(=O)c1cccnc1
Molecular Formula
C17H17ClFN3O2S
Molecular Weight
381.85
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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