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VEGFR-2-IN-23

Product Specifications

CAS Number

2411174-53-1

Target

Others, Apoptosis, VEGFR, MDM-2/p53

Related Pathways

Others, Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors

Bioactivity

VEGFR-2-IN-23 (compound 11b) is a highly potent and selective inhibitor of VEGFR-2, with an IC50 value of 0.34 nM. It demonstrates significant antitumor activity by inducing apoptosis and causing cell cycle arrest at the G1 phase [1].

Smiles

C(#N)C1=C(C=C(NC1=NN)C2=CC3=C(C=C2)C=CC=C3)C4=CC=C(N(=O)=O)C=C4

Molecular Formula

C22H15N5O2

Molecular Weight

381.39

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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