VEGFR-2-IN-23
Product Specifications
CAS Number
2411174-53-1
Target
Others, Apoptosis, VEGFR, MDM-2/p53
Related Pathways
Others, Angiogenesis, Apoptosis, Tyrosine Kinase/Adaptors
Bioactivity
VEGFR-2-IN-23 (compound 11b) is a highly potent and selective inhibitor of VEGFR-2, with an IC50 value of 0.34 nM. It demonstrates significant antitumor activity by inducing apoptosis and causing cell cycle arrest at the G1 phase [1].
Smiles
C(#N)C1=C(C=C(NC1=NN)C2=CC3=C(C=C2)C=CC=C3)C4=CC=C(N(=O)=O)C=C4
Molecular Formula
C22H15N5O2
Molecular Weight
381.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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