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HDAC-IN-42

Product Specifications

CAS Number

2454024-18-9

Target

Apoptosis, Others, HDAC

Related Pathways

Others, DNA Damage/DNA Repair, Apoptosis, Chromatin/Epigenetic

Bioactivity

HDAC-IN-42 (compound 14f) is a highly potent and selective inhibitor of histone deacetylase (HDAC) enzymes, with IC50 values of 0.19 μM for HDAC1 and 4.98 μM for HDAC6. It exhibits significant anticancer properties, inhibiting cell proliferation, inducing apoptosis, and causing cell cycle arrest specifically at the G2/M phase [1].

Smiles

C(OC1=CC(/C=C/C(NO)=O)=CC=C1)(=O)C2=CC=3C(OC2=O)=CC(OC)=CC3

Molecular Formula

C20H15NO7

Molecular Weight

381.34

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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