HDAC-IN-42
Product Specifications
CAS Number
2454024-18-9
Target
Apoptosis, Others, HDAC
Related Pathways
Others, DNA Damage/DNA Repair, Apoptosis, Chromatin/Epigenetic
Bioactivity
HDAC-IN-42 (compound 14f) is a highly potent and selective inhibitor of histone deacetylase (HDAC) enzymes, with IC50 values of 0.19 μM for HDAC1 and 4.98 μM for HDAC6. It exhibits significant anticancer properties, inhibiting cell proliferation, inducing apoptosis, and causing cell cycle arrest specifically at the G2/M phase [1].
Smiles
C(OC1=CC(/C=C/C(NO)=O)=CC=C1)(=O)C2=CC=3C(OC2=O)=CC(OC)=CC3
Molecular Formula
C20H15NO7
Molecular Weight
381.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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