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ERK5-IN-4

Product Specifications

CAS Number

1888305-17-6

Target

Others, ERK

Related Pathways

Others, MAPK

Bioactivity

ERK5-IN-4 (compound 34b) is a potent and specific inhibitor of extracellular signal-related kinase 5 (ERK5) activity, effectively inhibiting both full-length ERK5 and truncated ERK5 (ERK5 ΔTAD) kinase activity in HEK293 cells with IC50 values of 77 nM and 300 nM, respectively [1].

Smiles

C(=O)(C=1C=C(C(NC=2C=NN(C)C2)=O)NC1)C3=C(F)C(Cl)=CC=C3Cl

Molecular Formula

C16H11Cl2FN4O2

Molecular Weight

381.19

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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