ATX inhibitor 15
Product Specifications
CAS Number
2484811-52-9
Target
PDE, Others
Related Pathways
Metabolism, Others
Bioactivity
ATX inhibitor 15 (compound 30) is an indole-based carbamate derivative with a strong inhibitory effect on autotaxin (ATX), demonstrated by an IC50 of 2.17 nM. It effectively inhibits ATX activity in vivo, suppresses the expression of pro-fibrotic genes, and exhibits protective effects in Bleomycin-induced lung fibrosis in mice [1].
Smiles
N(C(NCC1=CC(Cl)=C(OC)C=C1)=O)C=2C=3C(N(CC)C2)=CC=C(C3)C4=NC(CN(CCO)CCO)=CS4
Molecular Formula
C27H32ClN5O4S
Molecular Weight
558.09
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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