H3R antagonist 2
Product Specifications
Target
Others, Monoamine Oxidase, Histamine Receptor, Cholinesterase (ChE)
Related Pathways
Immunology/Inflammation, Others, Neuroscience, GPCR/G Protein
Bioactivity
H3R antagonist 2 (Compound 23) is a multitarget histamine H3 receptor antagonist with inhibitory effects on acetylcholinesterase, butyrylcholinesterase, and human monoamine oxidase B (hMAO B) with IC50 values of 180 nM, 880 nM, and 775 nM, respectively. With a Ki of 170 nM for hH3R, it demonstrates favorable anti-neuropathic pain and memory-enhancing effects and can cross the blood-brain barrier (BBB) [1].
Molecular Formula
C24H29NO3
Molecular Weight
379.49
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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