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TLR7/8 antagonist 2

Product Specifications

Target

Others, TLR

Related Pathways

Immunology/Inflammation, Others

Bioactivity

TLR7/8 antagonist 2 (Compound 15) is a highly potent and orally active agonist of TLR7/8 with IC50 values of 4.9 nM for TLR7 and 0.6 nM for TLR8, making it a promising candidate for treating and investigating autoimmune diseases like lupus erythematosus, which involves inappropriate activation of TLR7 and TLR8. Consequently, TLR7/8 antagonist 2 is a valuable tool for autoimmune disease research [1].

Molecular Formula

C22H26FN5

Molecular Weight

379.47

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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