TLR7/8 antagonist 2
Product Specifications
Target
Others, TLR
Related Pathways
Immunology/Inflammation, Others
Bioactivity
TLR7/8 antagonist 2 (Compound 15) is a highly potent and orally active agonist of TLR7/8 with IC50 values of 4.9 nM for TLR7 and 0.6 nM for TLR8, making it a promising candidate for treating and investigating autoimmune diseases like lupus erythematosus, which involves inappropriate activation of TLR7 and TLR8. Consequently, TLR7/8 antagonist 2 is a valuable tool for autoimmune disease research [1].
Molecular Formula
C22H26FN5
Molecular Weight
379.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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