BF844
Product Specifications
CAS Number
1404506-35-9
Target
HSP, Others
Related Pathways
Others, Cytoskeletal Signaling, Metabolism
Bioactivity
BF844 is a chemical compound that demonstrates the ability to mitigate hearing loss in individuals with Usher Syndrome Type III (USH3) caused by the CLRN1 mutation (specifically N48K) . One of its mechanisms of action is the transportation of CLRN1 N48K to the plasma membrane. In vivo studies have shown that BF844 significantly preserves hearing [1].
Smiles
ClC1=C2C(N(CC(C)(C)O)N=C2C3=CC=CC=C3)=NN=C1C4=CC=CC=C4
Molecular Formula
C21H19ClN4O
Molecular Weight
378.85
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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