11β-HSD1-IN-6
Product Specifications
CAS Number
1303515-33-4
Target
Others, Dehydrogenase
Related Pathways
Others, Metabolism
Bioactivity
11β-HSD1-IN-6 is a potent inhibitor of 11β hydroxysteroid dehydrogenase enzymes (11β-HSDs), which catalyze the conversion of active glucocorticoids, corticosterone or cortisol, to their inactive forms, 11-dehydrocorticosterone (11-DHC) and cortisone. The compound specifically targets and inhibits 11β-HSD-1, modulating the interconversion of these glucocorticoids. [1]
Smiles
Cl.[H][C@]12Cc3ccc(cc3[C@@]1([H])CCCN2C(=O)c1ccc2nc[nH]c2c1)C#N
Molecular Formula
C21H19ClN4O
Molecular Weight
378.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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