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ASK1-IN-3

Product Specifications

CAS Number

2426705-19-1

Target

Others, MAPK, Apoptosis

Related Pathways

Apoptosis, Others, MAPK

Bioactivity

ASK1-IN-3 is a highly potent and selective inhibitor of ASK1 kinase, demonstrating an IC 50 of 33.8 nM. This compound also exhibits inhibitory effects on various cell cycle regulating kinases. ASK1-IN-3 showcases remarkable induction of apoptosis in HepG2 cancer cells and displays potent activity in arresting the cell cycle [1].

Smiles

[C@H](CO)(C)N1C(=NN=C1)C=2N=C(NC(NC=3C=C4N(N3)C=CC=C4)=O)C=CC2

Molecular Formula

C18H18N8O2

Molecular Weight

378.39

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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