ASK1-IN-3
Product Specifications
CAS Number
2426705-19-1
Target
Others|||MAPK|||Apoptosis
Related Pathways
Apoptosis|||Others|||MAPK
Bioactivity
ASK1-IN-3 is a highly potent and selective inhibitor of ASK1 kinase, demonstrating an IC 50 of 33.8 nM. This compound also exhibits inhibitory effects on various cell cycle regulating kinases. ASK1-IN-3 showcases remarkable induction of apoptosis in HepG2 cancer cells and displays potent activity in arresting the cell cycle [1].
Smiles
[C@H](CO)(C)N1C(=NN=C1)C=2N=C(NC(NC=3C=C4N(N3)C=CC=C4)=O)C=CC2
Molecular Formula
C18H18N8O2
Molecular Weight
378.39
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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