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USP15-IN-1

Product Specifications

CAS Number

2260826-16-0

Target

DUB

Related Pathways

DNA Damage/DNA Repair, Ubiquitination, Cell Cycle/Checkpoint

Purity

0.9981

Bioactivity

USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 μM) with high antiproliferative activity against non-small cell lung cancer and leukemia cells. As an interacting protein of cGAS, USP15 promotes cGAS to recognize DNA and activate downstream signaling pathways.

Smiles

OCCNC(=O)c1ccc2[nH]c3CN(CCc3c2c1)C(=O)Cc1ccccc1

Molecular Formula

C22H23N3O3

Molecular Weight

377.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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