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HDAC8-IN-2

Product Specifications

Target

Parasite, Others, HDAC

Related Pathways

Chromatin/Epigenetic, Others, Microbiology/Virology, DNA Damage/DNA Repair

Bioactivity

HDAC8-IN-2 (compound 5o) is a potent HDAC8 inhibitor with IC50 values of 0.27 μM and 0.32 μM for smHDAC8 (Schistosoma mansoni histone deacetylase 8) and hHDAC8, respectively. It effectively kills schistosome larvae and significantly reduces egg laying in adult worm pairs [1].

Molecular Formula

C21H16N2O5

Molecular Weight

376.36

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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