HDAC8-IN-2
Product Specifications
Target
Parasite, Others, HDAC
Related Pathways
Chromatin/Epigenetic, Others, Microbiology/Virology, DNA Damage/DNA Repair
Bioactivity
HDAC8-IN-2 (compound 5o) is a potent HDAC8 inhibitor with IC50 values of 0.27 μM and 0.32 μM for smHDAC8 (Schistosoma mansoni histone deacetylase 8) and hHDAC8, respectively. It effectively kills schistosome larvae and significantly reduces egg laying in adult worm pairs [1].
Molecular Formula
C21H16N2O5
Molecular Weight
376.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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