NFATc1-IN-1
Product Specifications
CAS Number
1912422-56-0
Target
RANKL/RANK, Others
Related Pathways
Others, NF-κB
Purity
0.9998
Bioactivity
NFATc1-IN-1 (also known as compound A04) is a highly effective inhibitor of osteoclast formation induced by RANKL, with an IC50 of 1.57 μM. It exerts its anti-osteoclastogenic effects by attenuating the RANKL-induced nuclear translocation of NFATc1. Due to its remarkable properties, NFATc1-IN-1 holds significant potential for advancing research related to osteoclastic diseases [1].
Smiles
C(NC1=C(F)C=C(I)C=C1)(=O)C2=C(O)C=CC(F)=C2
Molecular Formula
C13H8F2INO2
Molecular Weight
375.11
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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