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NFATc1-IN-1

Product Specifications

CAS Number

1912422-56-0

Target

RANKL/RANK, Others

Related Pathways

Others, NF-κB

Purity

0.9998

Bioactivity

NFATc1-IN-1 (also known as compound A04) is a highly effective inhibitor of osteoclast formation induced by RANKL, with an IC50 of 1.57 μM. It exerts its anti-osteoclastogenic effects by attenuating the RANKL-induced nuclear translocation of NFATc1. Due to its remarkable properties, NFATc1-IN-1 holds significant potential for advancing research related to osteoclastic diseases [1].

Smiles

C(NC1=C(F)C=C(I)C=C1)(=O)C2=C(O)C=CC(F)=C2

Molecular Formula

C13H8F2INO2

Molecular Weight

375.11

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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