What is the catalog number for GSK2646264?

The catalog number for GSK2646264 is T61527.

What sizes are available for GSK2646264?

GSK2646264 is available in the following size(s): 25 mg, 50 mg.

How many pack sizes does GSK2646264 come in?

GSK2646264 is available in 2 different pack sizes.

Is GSK2646264 in stock?

GSK2646264 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures GSK2646264?

GSK2646264 is manufactured by Molfinity.

What is the estimated delivery time for GSK2646264?

Estimated delivery time for GSK2646264 is approximately 10 business day(s), depending on your location.

GSK2646264

Product Specifications

CAS Number

1398695-47-0

Target

Others, VEGFR, GSK-3, JAK, LRRK2, Aurora Kinase, Syk, Src

Related Pathways

Autophagy, Cell Cycle/Checkpoint, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, Stem Cells, Others, PI3K/Akt/mTOR signaling, Angiogenesis, JAK/STAT signaling

Bioactivity

GSK2646264 (Compound 44) is a highly effective and specific inhibitor of spleen tyrosine kinase (SYK) with a pIC50 of 7.1. It also inhibits multiple kinases, including LCK (pIC50 5.4), LRRK2 (pIC50 5.4), GSK3β (pIC50 5.3), JAK2 (pIC50 5), VEGFR2 (pIC50 4.5), Aurora B (pIC50 <4.6), and Aurora A (pIC50 <4.3) . Notably, GSK2646264 demonstrates skin penetrability, reaching both the epidermis and dermis [1].