EGFR-IN-51
Product Specifications
CAS Number
2418549-32-1
Target
Others, Apoptosis, EGFR
Related Pathways
Apoptosis, Others, Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis
Bioactivity
EGFR-IN-51 (Compound 6) is a highly potent EGFR inhibitor with IC50 values of 0.493, 102.60, and 461.63 μM against EGFR, EGFR L858R-TK, and EGFR T790M-TK targets, respectively. Additionally, EGFR-IN-51 exhibits cytotoxicity against cancer cell lines, effectively inducing apoptosis [1].
Smiles
N(C(NC=1C=C2C(=CC1)OCO2)=S)C=3C4=C(N=C5C3C=CC=C5)C=CC=C4
Molecular Formula
C21H15N3O2S
Molecular Weight
373.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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