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Rho-Kinase-IN-2

Product Specifications

CAS Number

2573071-18-6

Target

Others, ROCK

Related Pathways

Others, Cell Cycle/Checkpoint, Cytoskeletal Signaling, Stem Cells

Bioactivity

Rho-Kinase-IN-2 (Compound 23) is an orally active and selective inhibitor of Rho Kinase (ROCK) with CNS penetration, exhibiting a high affinity for ROCK2 with an IC50 of 3 nM. This compound is of potential interest for further investigations in Huntington's disease research [1].

Smiles

FC=1C(N2C[C@@H](C)N(C(N[C@H](C)C3=CC(OC)=CC=C3)=O)CC2)=CC=NC1

Molecular Formula

C20H25FN4O2

Molecular Weight

372.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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