Rho-Kinase-IN-2
Product Specifications
CAS Number
2573071-18-6
Target
Others, ROCK
Related Pathways
Others, Cell Cycle/Checkpoint, Cytoskeletal Signaling, Stem Cells
Bioactivity
Rho-Kinase-IN-2 (Compound 23) is an orally active and selective inhibitor of Rho Kinase (ROCK) with CNS penetration, exhibiting a high affinity for ROCK2 with an IC50 of 3 nM. This compound is of potential interest for further investigations in Huntington's disease research [1].
Smiles
FC=1C(N2C[C@@H](C)N(C(N[C@H](C)C3=CC(OC)=CC=C3)=O)CC2)=CC=NC1
Molecular Formula
C20H25FN4O2
Molecular Weight
372.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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