APE1-IN-1
Product Specifications
CAS Number
524708-03-0
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/Checkpoint, DNA Damage/DNA Repair
Purity
0.985
Bioactivity
APE1-IN-1 is a potent inhibitor of purine/pyrimidine endonuclease 1 (APE1) that crosses the blood-brain barrier, exhibits potential antitumor activity, and enhances the cytotoxicity of the alkylating agent [methyl methanesulfonate] on cancer cells.
Smiles
CC(C)N1CCc2c(C1)sc(NC(C)=O)c2-c1nc2ccccc2s1
Molecular Formula
C19H21N3OS2
Molecular Weight
371.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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