TP0480066
Product Specifications
CAS Number
2245693-15-4
Target
Others, Topoisomerase, Antibacterial
Related Pathways
Microbiology/Virology, Others, DNA Damage/DNA Repair
Bioactivity
TP0480066, a selective topoisomerase II inhibitor, demonstrates excellent inhibitory activity against DNA gyrase (IC50 = 1.10 nM) and topo IV (IC50 = 62.89 nM) . This compound exhibits potent efficacy against multiple bacterial species, including drug-resistant strains. Moreover, TP0480066 displays significant inhibitory activity against N. gonorrhoeae, making it suitable for research on gonorrhea [1] [2].
Smiles
N(C)C1=C2C(C(O)=C(C(NC3=CC=C(C(O)=O)C=C3)=O)C(=O)N2)=CC(F)=C1
Molecular Formula
C18H14FN3O5
Molecular Weight
371.32
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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