NHE3-IN-3
Product Specifications
CAS Number
543734-50-5
Target
Others, Sodium Channel
Related Pathways
Others, Membrane transporter/Ion channel
Bioactivity
NHE3-IN-3 (Compound 1) is a potent inhibitor of isoform 3 of the Na+/H+ exchanger (NHE3), exhibiting pIC50 values of 6.2 and 6.6 against human and rat NHE3, respectively, and demonstrates exceptional oral bioavailability of 98% in Sprague–Dawley rats [1].
Smiles
CN1CC(C=2C(C1)=C(Cl)C=C(Cl)C2)C3=CC(S(N)(=O)=O)=CC=C3
Molecular Formula
C16H16Cl2N2O2S
Molecular Weight
371.28
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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