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EV-A71-IN-1

Product Specifications

CAS Number

2413648-96-9

Target

Others, Virus Protease

Related Pathways

Others, Microbiology/Virology

Bioactivity

EV-A71-IN-1 is a potent inhibitor of the human enterovirus A71 (EV-A71) capsid protein, with an EC50 of 0.27 μM against EV-A71. Acting as a capsid binder, EV-A71-IN-1 disrupts the crucial interaction between the viral VP1 protein and the host receptor hSCARB2. It displays broad-spectrum antiviral activity against various human enteroviruses, while being non-toxic to human cells (CC50 > 56.2 μM) [1].

Smiles

N(C1=NC(C=2N3C(=NC2)N=CC=C3)=CS1)C4=CC=C(C=C4)C5=CC=CC=C5

Molecular Formula

C21H15N5S

Molecular Weight

369.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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