EV-A71-IN-1
Product Specifications
CAS Number
2413648-96-9
Target
Others, Virus Protease
Related Pathways
Others, Microbiology/Virology
Bioactivity
EV-A71-IN-1 is a potent inhibitor of the human enterovirus A71 (EV-A71) capsid protein, with an EC50 of 0.27 μM against EV-A71. Acting as a capsid binder, EV-A71-IN-1 disrupts the crucial interaction between the viral VP1 protein and the host receptor hSCARB2. It displays broad-spectrum antiviral activity against various human enteroviruses, while being non-toxic to human cells (CC50 > 56.2 μM) [1].
Smiles
N(C1=NC(C=2N3C(=NC2)N=CC=C3)=CS1)C4=CC=C(C=C4)C5=CC=CC=C5
Molecular Formula
C21H15N5S
Molecular Weight
369.44
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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