SIRT5 inhibitor 4
Product Specifications
CAS Number
708992-34-1
Target
Sirtuin
Related Pathways
Chromatin/Epigenetic, DNA Damage/DNA Repair
Purity
0.9997
Bioactivity
SIRT5 inhibitor 4 (compound 11) is a dose-dependent and selective SIRT5 (Sirtuin5) inhibitor with an IC50 value of 26.4 μM for SIRT5 and no inhibitory effect on SIRT1/2/3 isoforms at 400 μM, with anticancer potential.
Smiles
O=C(O)C1=CC=C(C=C1O)NC2=NC(=CS2)C=3C=CC(=CC3)NC(=O)C
Molecular Formula
C18H15N3O4S
Molecular Weight
369.39
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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