Zolunicant
Product Specifications
CAS Number
188125-42-0
Target
Parasite|||AChR
Related Pathways
Microbiology/Virology|||Neuroscience
Bioactivity
Zolunicant (MM-110) is a potent nicotinic ?3?4 receptor inhibitor with an IC50 of 0.90 ?M, showing promise in combating addiction. It effectively reduces self-administration of addictive agents such as morphine, cocaine, methamphetamine, nicotine, and ethanol in rat models, indicating its potential as a treatment for various forms of drug abuse [1]. Additionally, Zolunicant exhibits strong leishmanicidal activity against Leishmania amazonensis, expanding its therapeutic prospects [2].
Smiles
C(OC)(=O)[C@]12[C@]3([N@](CC(C1)(C[C@@H]3CCOC)[H])CCC4=C2NC=5C4=CC=CC5)[H]
Molecular Formula
C22H28N2O3
Molecular Weight
368.47
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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