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Trk-IN-7

Product Specifications

Target

Others, Trk receptor

Related Pathways

Tyrosine Kinase/Adaptors, Others

Bioactivity

Trk-IN-7 (compound I-6) is a highly potent TRK inhibitor, with IC50 values of 0.25-10 nM for TRKA, TRKB, and TRKC, respectively. It also shows significant inhibition of EML4-ALK (IC50 <15 nM) and ALK mutations G1202R, C1156Y, R1275Q, F1174L, L1197M, and G1269A (IC50 = 5-50 nM) [1].

Molecular Formula

C18H17FN6O2

Molecular Weight

368.36

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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