Trk-IN-7
Product Specifications
Target
Others|||Trk receptor
Related Pathways
Tyrosine Kinase/Adaptors|||Others
Bioactivity
Trk-IN-7 (compound I-6) is a highly potent TRK inhibitor, with IC50 values of 0.25-10 nM for TRKA, TRKB, and TRKC, respectively. It also shows significant inhibition of EML4-ALK (IC50 <15 nM) and ALK mutations G1202R, C1156Y, R1275Q, F1174L, L1197M, and G1269A (IC50 = 5-50 nM) [1].
Molecular Formula
C18H17FN6O2
Molecular Weight
368.36
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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