HIF-1/2α-IN-1
Product Specifications
Target
Others, HIF/HIF Prolyl-Hydroxylase
Related Pathways
Others, Chromatin/Epigenetic, Metabolism
Bioactivity
HIF-1/2α-IN-1, an orally active compound, functions as an inhibitor of HIF-2α. Its inhibitory effect on HIF-2α activity is significant, with an IC 50 value of 0.92 μM. Furthermore, HIF-1/2α-IN-1 has the ability to decrease HIF-1α levels. This compound is particularly valuable for research on clear cell renal cell carcinoma (ccRCC) [1].
Molecular Formula
C17H16N6O4
Molecular Weight
368.35
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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