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TOPK-p38/JNK-IN-1

Product Specifications

CAS Number

2745108-35-2

Target

JNK, Others

Related Pathways

MAPK, Others

Bioactivity

TOPK-p38/JNK-IN-1 (Compound B12) is an orally active inhibitor of the TOPK-p38/JNK signaling pathway, exhibiting an IC50 of 2.14 μM for NO production inhibition. It demonstrates anti-inflammatory properties by inhibiting downstream protein phosphorylation and preventing TOPK degradation [1].

Smiles

N(C(NC1=CC(C(F)(F)F)=CC=C1)=O)C2=C(OC)C=C(O)C(C(C)=O)=C2

Molecular Formula

C17H15F3N2O4

Molecular Weight

368.31

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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