PI-103 Hydrochloride
Product Specifications
CAS Number
371935-79-4
Target
Akt, Cell Cycle Arrest, Apoptosis, DNA-PK, Autophagy, mTOR, PI3K, Mitochondrial Metabolism
Related Pathways
PI3K/Akt/mTOR signaling, Cell Cycle/Checkpoint, Autophagy, Cytoskeletal Signaling, Apoptosis, Metabolism, DNA Damage/DNA Repair
Purity
0.9707
Bioactivity
PI-103 Hydrochloride is a dual PI3K/Akt and mTOR inhibitor exhibiting nM-level inhibition of p110α, p110β, p110δ, p110γ, DNA-PK, mTORC1, and mTORC2. PI-103 induces autophagy, mitochondrial apoptosis, and cell cycle arrest, making it suitable for leukaemia research.
Smiles
Cl.Oc1cccc(c1)-c1nc(N2CCOCC2)c2oc3ncccc3c2n1
Molecular Formula
C19H17ClN4O3
Molecular Weight
384.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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