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Cdc7-IN-18

Product Specifications

CAS Number

2562329-14-8

Target

Others, CDK

Related Pathways

Others, Cell Cycle/Checkpoint

Bioactivity

Cdc7-IN-18 (compound 1-2) is a highly effective inhibitor of the CDC7 enzyme, with an IC50 value of 1.29 nM for the Cdc7/DBF4 enzyme. Additionally, this compound exhibits strong antiproliferative activities, with an IC50 value of 53.62 nM in COLO205 cells [1].

Smiles

O=C1C2=C(C3=C(S2)C=4C(CCC3)=NNC4)NC(=N1)[C@@H]5N6CCC(C5)CC6

Molecular Formula

C19H21N5OS

Molecular Weight

367.47

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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