4-PQBH
Product Specifications
CAS Number
2243355-51-1
Target
Others, Apoptosis, NR4A
Related Pathways
Apoptosis, Endocrinology/Hormones, Others
Purity
0.9908
Bioactivity
4-PQBH is a potent Nur77-binding agent with antitumour activity.4-PQBH inhibits xenograft tumours through Nur77-mediated endoplasmic stress and autophagy by broadly inducing cysteoaspartase-independent cytoplasmic vacuolisation and parapetaloid ptosis.4-PQBH is used in the study of hepatocellular carcinoma.4-PQBH is a potent Nur77-binding agent with antitumour activity.
Smiles
O=C(NN=CC=1C=CN=CC1)C2=CC=C(C=C2)NC=3C=CN=C4C=CC=CC43
Molecular Formula
C22H17N5O
Molecular Weight
367.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
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