OD36 hydrochloride
Product Specifications
CAS Number
2387510-88-3
Target
ALK, TGF-beta/Smad, RIP kinase
Related Pathways
NF-κB, Angiogenesis, Stem Cells, Tyrosine Kinase/Adaptors, Apoptosis
Purity
0.9985
Bioactivity
OD36 hydrochloride (OD-36 hydrochloride) is a potent RIPK2 inhibitor with an IC50 of 5.3 nM.OD36 hydrochloride is a macrocyclic inhibitor that binds efficiently to the ATP pocket of the ALK2 kinase and effectively antagonizes mutant ALK2 signaling and osteogenic differentiation.OD36 hydrochloride targets ALK2. OD36 hydrochloride targets ALK2 with a KD of 37 nM.
Smiles
Cl.ClC=1C=C2OCCOCCN=C3C=CN4N=CC(C(C1)=C2)=C4N3
Molecular Formula
C16H16Cl2N4O2
Molecular Weight
367.23
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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