A-674563 2HCl (552325-73-2 (fb-2hcl) )
Product Specifications
Target
PKA, PKC, ERK, Akt, CDK
Related Pathways
Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint, Chromatin/Epigenetic, MAPK
Purity
0.9957
Bioactivity
A-674563 2HCl is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
Smiles
Cl.Cl.Cc1n[nH]c2ccc(cc12)-c1cncc(OC[C@@H](N)Cc2ccccc2)c1
Molecular Formula
C22H24Cl2N4O
Molecular Weight
431.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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