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A-674563

Product Specifications

CAS Number

552325-73-2

Target

ERK, GSK-3, Akt, PKA, CDK

Related Pathways

Stem Cells, Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, Cell Cycle/Checkpoint, Tyrosine Kinase/Adaptors, MAPK

Purity

0.9921

Bioactivity

A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.

Smiles

Cl.Cc1n[nH]c2ccc(cc12)-c1cncc(OC[C@@H](N)Cc2ccccc2)c1

Molecular Formula

C22H22N4O

Molecular Weight

358.44

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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