Bromodomain inhibitor-10
Product Specifications
CAS Number
1870849-58-3
Target
Others, Epigenetic Reader Domain
Related Pathways
Chromatin/Epigenetic, Others
Bioactivity
Bromodomain inhibitor-10 (compound 128) is a highly potent bromodomain activity inhibitor, exhibiting strong binding affinity with Kd values of 15.0 nM and 2500 nM for BRD4-1 and BRD4-2, respectively. It also effectively inhibits the production of IL12p40 [1].
Smiles
C(NC=1C=C2C(=CC1)NC(=O)C=C2C)(=O)C3=C(N=CC=C3)N4CCOCC4
Molecular Formula
C20H20N4O3
Molecular Weight
364.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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