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IDO1/TDO-IN-1

Product Specifications

CAS Number

2379527-72-5

Target

Others, IDO, Apoptosis, Indoleamine 2,3-Dioxygenase (IDO), Bcl-2 Family

Related Pathways

Metabolism, Apoptosis, Others

Bioactivity

IDO1/TDO-IN-1 (30) is a highly effective inhibitor of IDO1 and TDO enzymes, acting through uncompetitive (Ki = 0.23 μM) and competitive (Ki = 0.73 μM) mechanisms, respectively. This compound exhibits significant capacity to induce cell apoptosis via the potential mitochondria-mediated Bcl-2/Bax pathway [1].

Smiles

O=C1C=2C(C3=C(C1=O)C(COC(C)=O)=CO3)=CC=C4C2C=CC(=O)C4(C)C

Molecular Formula

C21H16O6

Molecular Weight

364.35

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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