DNA-PK-IN-6
Product Specifications
CAS Number
2711810-41-0
Target
Others, DNA-PK
Related Pathways
Others, PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair
Bioactivity
DNA-PK-IN-6, a robust DNA-PK inhibitor, effectively hampers the activity of DNA-PKcs, thereby significantly impairing the DNA repair mechanism in tumors and instigating apoptosis in cells. Additionally, DNA-PK-IN-6 amplifies the responsiveness of tumor tissues to radiotherapy, overcomes the challenge of drug resistance, and augments its inhibitory impact on a diverse range of solid and hematological tumors[1].
Smiles
CN1C2=C3N(C1=O)CCCCCC=4N5C=C(N=C(N3)N=C2)C(C)=CC5=NC4
Molecular Formula
C19H21N7O
Molecular Weight
363.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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