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Peficitinib hydrochloride

Product Specifications

CAS Number

1353219-06-3

Target

Others, JAK

Related Pathways

Tyrosine Kinase/Adaptors, Others, Chromatin/Epigenetic, JAK/STAT signaling, Stem Cells, Angiogenesis

Bioactivity

Peficitinib hydrochloride, also known as ASP015K, is an orally active JAK inhibitor compound. It exhibits inhibitory activity against JAK1, JAK2, JAK3, and Tyk2, with IC 50 values of 3.9, 5.0, 0.7, and 4.8 nM, respectively.

Smiles

Cl.[H][C@]12CC3C[C@]([H])(CC(O)(C3)C1)[C@H]2Nc1c(cnc2[nH]ccc12)C(N)=O

Molecular Formula

C18H23ClN4O2

Molecular Weight

362.86

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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